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. 2018 May 25;18:596. doi: 10.1186/s12885-018-4453-z

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Evaluation of CD4+ and CD8+ cells infiltration around the cancer tissue (HF-1-05). a Three areas in different distances (circle) from the residual cancer (dot-line circle) were evaluated. b, c Infiltration of CD4+ and CD8+ cells was significant in the fibrosis near the residual cancer tissue (area 3) and it became obscure as the areas receded from the cancer tissue