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. 2018 May 25;18:76. doi: 10.1186/s12935-018-0570-7

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Overexpression of SOX2OT (NR_004053) promoted esophageal cancer cells growth. a, b Forced expression of SOX2OT promoted esophageal cancer cells growth with or without DDP treatment. CCK8 assay was performed to determine the cell growth of ESCC cells transfected with pcDNA3.1 and SOX2OT-pcDNA3.1. c Overexpression of SOX2OT enhanced esophageal cancer cells proliferation. Edu assay was used to determine cell proliferation of KYSE150 and KYSE450 cells after transfected with plasmids. The bar chart represented the ratio of Edu-positive cells. *P < 0.05, **P < 0.01, ***P < 0.001