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. 2018 May 25;18:76. doi: 10.1186/s12935-018-0570-7

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Ectopic expression of SOX2 promoted SOX2OT expression at transcriptional level. a, c qPCR was used to detect SOX2 mRNA and SOX2OT expression. Overexpression of SOX2 promoted SOX2OT expression in EC109 and EC9706 cells. b, d Luciferase reporter assay showed that SOX2 could increase the luciferase activity of SOX2OT-pGL3/Basic. **P < 0.01, ***P < 0.001