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. 2018 May 25;15:95. doi: 10.1186/s12985-018-1001-z

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — a, phylogenetic tree analysis of polyprotein of different Aichivirus C (PKV-1) strains. Based on phylogenetic analysis with whole genome sequences, kobuviruses form three genogroups. The kobuviruses detected in this study (Black dot) were categorized into two different genogroups. One strain (ISU20245) is most closely related to a US strain reported in 2011, and three additional strains (ISU20448, ISU25220, and ISU41447) were grouped into to anther genogroup and were most closely related to Chinese and Thai strains implicated in swine diarrhea. b, Aichivirus C (PKV-1) alignment (aa position 1183–1224 of polyprotein with PKV/US/ISU25220/2015 as reference) demonstrating insertions and deletions among different strains