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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Magn Reson Imaging. 2018 Mar 12;50:68–77. doi: 10.1016/j.mri.2018.03.011

Figure 2.

Figure 2

(Top plot) The labeling function (inp(t)) is plotted for the first 5 seconds of the MRF ASL experiment. The labeling function is equal to one during application of pCASL labeling pulses only. (2nd plot) The arterial bolus magnetization is plotted for the first 5 seconds of the MRF ASL experiment. This is simulated with a arterial bolus time-to-peak of 1.2 seconds and includes dispersion. (3rd plot) The tissue bolus magnetization is plotted for the first 5 seconds of the MRF ASL experiment. This is simulated with a tissue bolus time-to-peak of 1.5 seconds, includes dispersion, and a CBF of 65 ml/min/100g. (4th plot) The simulated signal for this two compartment model is plotted for the first 100 images of the MRF ASL experiment. The timing of the RF excitation for data acquisition are noted with ‘x’. (Bottom plot) Signals from two representative tissues are plotted. Tissue 1 has a CBF of 65 ml/min/100g, CBV of 0.02, arterial time-to-peak of 1.2 s, and tissue time-to-peak of 1.5 s, T1 of 1.4 s. Tissue 2 has a CBF of 40 ml/min/100g, CBV of 0.001, arterial time-to-peak of 1.7 s, and tissue time-to-peak of 1.9 s, T1 of 1.08 s.