Figure 4.
Expected times – 10th, 25th and 50th (percentile) - from GFR/proteinuria risk characterization (study baseline) to clinical composite event (50% GFR decline, renal replacement therapy, or GFR less than 15 mL/min/1.73m2), for six GFR/proteinuria risk stages, by CKD diagnosis. Estimated event times are generated from an accelerated failure time model using a conventional generalized gamma distribution with seven beta indicator parameters: six risk stages (A-F) and glomerular CKD. Time to event is from baseline (time at which risk level was defined). Event is defined as RRT, GFR<15mL/min/173m2 or 50% GFR decline.