Figure 3. Effects of inhibitors of ABCB1 and GST on sensitivity to BH in KPUM-YY1 and KPUM-YY1R cells. Cells were treated with BH for 96 h with or without 5 μM cyclosporin A (A), 10 μM verapamil (B), 5 μM PSC833 (C), 5 μM C-4 (D) or 30 μM ethacrynic acid (E). Cell viability was evaluated by a modified MTT assay. Growth inhibition by BH was at least partly reversed by each inhibitor for ABCB1 or GST in KPUM-YY1R cells.
