Table 2.

Name, source and bioactivities of polycyclic GMs

Number	Name	Bioactivity	Source	References
41	Applanatumol V	Inhibitory activities against COX-1 and COX-2	G. applanatum	[32]
42	Applanatumol W	Inhibitory activities against COX-1 and COX-2	G. applanatum	[32]
43	Applanatumol X	Inhibitory activities against COX-1 and COX-2	G. applanatum	[32]
44	Applanatumol Y	Inhibitory activities against COX-1 and COX-2	G. applanatum	[32]
45	Applanatumol Z	Inhibitory activities against COX-1, COX-2	G. applanatum	[32]
46	Applanatumol Z2	Inhibitory activities against COX-1, COX-2	G. applanatum	[32]
47	Applanatumol K	Inhibitory activities against COX-1 and COX-2	G. applanatum	[32]
48	Applanatumol L	Inhibitory activities against COX-1 and COX-2	G. applanatum	[32]
49	Applanatumol M	Inhibitory activities against COX-1 and COX-2	G. applanatum	[32]
50	Applanatumol N	Inhibitory activities against COX-1 and COX-2	G. applanatum	[32]
51	Applanatumol O	Inhibitory activities against COX-1 and COX-2	G. applanatum	[32]
52	Chizhiol A	Inhibitory activities against COX-1 and COX-2	G. lucidum	[39]
53	Ganotheaecoloid L	Inhibitory activities against COX-1 and COX-2	G. theaecolum	[40]
54	(+)-Ganotheaecoloid M	Inhibitory activities against COX-1 and COX-2	G. theaecolum	[40]
55	(−)-Ganotheaecoloid N	Inhibitory activities against COX-1 and COX-2	G. theaecoloum	[40]
56	Petchiene A	Inhibitory activities against COX-1 and COX-2	G. petchii	[41]
57	Lingzhine C	Promote proliferation of neural stem cells (NSCs)	G. lucidum	[38]
58	(±)-Lingzhine B	Inhibit NSC proliferation	G. lucidum	[38]
59	(−)-Ganotheaecoloid A	Inhibitory activities against COX-2	G. theaecolum	[40]
60	(−)-Ganotheaecoloid B	Inhibitory activities against COX-2	G. theaecolum	[40]
61	Ganotheaecoloid C	Inhibitory activities against COX-2	G. theaecolum	[40]
62	Ganotheaecoloid D	Inhibitory activities against COX-2	G. theaecolum	[40]
63	Ganotheaecoloid E	Inhibitory activities against COX-2	G. theaecolum	[40]
64	(−)-Ganotheaecoloid F	Inhibitory activities against COX-2	G. theaecolum	[40]
65	Ganotheaecoloid G	Inhibitory activities against COX-2	G. theaecolum	[40]
66	Ganotheaecoloid H	Inhibitory activities against COX-2	G. theaecolum	[40]
67	Ganotheaecoloid I	Inhibitory activities against COX-2	G. theaecolum	[40]
68	(+)-Ganotheaecoloid J	COX-2 inhibitory activity (IC50: 9.96 μM)	G. theaecolum	[40]
69	Ganotheaecoloid K	Inhibitory activities against COX-2	G. theaecolum	[40]
70	(+)-Cochlearin A	Antioxidant activity	G. cochlear	[30]
71	Spiroapplanatumine A	Inhibitory activities against JAK3 kinase	G. applanatum	[42]
72	Spiroapplanatumine C	Inhibitory activities against JAK3 kinase	G. applanatum	[42]
73	Spiroapplanatumine E	Inhibitory activities against JAK3 kinase	G. applanatum	[42]
74	Spiroapplanatumine G	Inhibitory activities against JAK3 kinase	G. applanatum	[42]
75	Spiroapplanatumine I	Inhibitory activities against JAK3 kinase	G. applanatum	[42]
76	Spiroapplanatumine B	Inhibitory activities against JAK3 kinase	G. applanatum	[42]
77	Spiroapplanatumine D	Inhibitory activities against JAK3 kinase (IC50: 7.0 ± 3.2 μM)	G. applanatum	[42]
78	Spiroapplanatumine F	Inhibitory activities against JAK3 kinase (IC50: 34.8 ± 21.1 μM)	G. applanatum	[42]
79	Spiroapplanatumine H	Inhibitory activities against JAK3 kinase	G. applanatum	[42]
80	Spiroapplanatumine J	Inhibitory activities against JAK3 kinase	G. applanatum	[42]
81	Spiroapplanatumine K	Inhibitory activities against JAK3 kinase	G. applanatum	[42]
82	Spiroapplanatumine L	Inhibitory activities against JAK3 kinase	G. applanatum	[42]
83	Spiroapplanatumine M	Inhibitory activities against JAK3 kinase	G. applanatum	[42]
84	(+)-Spiroapplanatumine N	Inhibitory activity against JAK3 kinase	G. applanatum	[42]
85	Spiroapplanatumine O	Inhibitory activities against JAK3 kinase	G. applanatum	[42]
86	(−)-Spiroapplanatumine N	Inhibitory activities against JAK3 kinase	G. applanatum	[42]
87	Spiroapplanatumine P	Inhibitory activities against JAK3 kinase	G. applanatum	[42]
88	Spiroapplanatumine Q	Inhibitory activities against JAK3 kinase	G. applanatum	[42]
89	(+)- Spirolingzhine A	Protective effects for NSC	G. lucidum	[38]
90	(+)-Spirolingzhine B	Protective effects for NSC	G. lucidum	[38]
91	(+)-Spirolingzhine C	Protective effects for NSC	G. lucidum	[38]
92	Spirolingzhine D	Protective effects for NSC	G. lucidum	[38]
93	(±)-Ganoderin A	Antioxidant activity	G. cochlear	[15]
94	Applanatumol H	Inhibitory activities against COX-1, COX-2	G. applanatum	[32]
95	Applanatumol I	Inhibitory activities against COX-1, COX-2	G. applanatum	[32]
96	Applanatumol J	Inhibitory activities against COX-1, COX-2	G. applanatum	[32]
97	Applanatumol D	Inhibitory activities against COX-1, COX-2	G. applanatum	[32]
98	Applanatumol E	Inhibitory activities against COX-1, COX-2	G. applanatum	[32]
99	Applanatumol J	Inhibitory activities against COX-1, COX-2	G. applanatum	[32]
100	Applanatumol F	Inhibitory activities against J COX-1, COX-2	G. applanatum	[32]
101	Lingzhilactone A	Renoprotective effect	G. lucidum	[43]
102	Lingzhilactone B	Renoprotective effect	G. lucidum	[43]
103	Lingzhilactone C	Renoprotective effect	G. lucidum	[43]
104	Applanatumol Z3	Inhibitory activities against JAK3 kinase	G. applanatum	[32]
105	Applanatumol Z4	Inhibitory activities against JAK3 and DDR1 kinases	G. applanatum	[32]
106	Applanatumol C	Inhibitory activities against JAK3 and DDR1 kinases	G. applanatum	[32]
107	(−)-Lingzhiol	Renoprotective effect	G. lucidum	[44]
108	(±)-Ganocochlearin A	Antioxidant activity	G. cochlear	[15]
109	(±)-Ganocochlearin B	Antioxidant activity	G. cochlear	[15]
110	(±)-Ganocochlearin C	Antioxidant activity	G. cochlear	[15]
111	(±)-Ganocochlearin D	Antioxidant activity	G. cochlear	[15]
112	Lingzhine D	Anti-BuChE activity	G. lucidum	[38]
113	(±)-Ganocin A	Anti-BuChE activity	G. cochlear	[45]
114	(±)-Ganocin B	Anti-BuChE activity	G. cochlear	[45]
115	(±)-Ganocin C	Anti-BuChE activity	G. cochlear	[45]
116	(±)-Ganocin D	Anti-BuChE activity	G. cochlear	[45]
117	Cochlearol A	Renoprotective effect	G. cochlear	[46]
118	Cochlearol B	Renoprotective effect	G. cochlear	[46]
119	Applanatumol A	Anti-renal fibrosis	G. applanatum	[18]
120	(±)-Applanatumol B	Anti-renal fibrosis	G. applanatum	[18]