Table 1.
Expression of miR-324-3p in human gastric cancer and the clinicopathological characteristics of the patients
| Characteristics | Number (%) | miR-324-3p expression | P value | Smad4 expression | P value | ||
|---|---|---|---|---|---|---|---|
| High group | Low group | High group | Low group | ||||
| Age (years) | |||||||
| ≥ 60 | 43 (63.2%) | 23 | 20 | 0.451 | 21 | 22 | 0.801 |
| < 60 | 25 (36.8%) | 11 | 14 | 13 | 12 | ||
| Gender | |||||||
| Male | 37 (54.4%) | 18 | 19 | 0.808 | 20 | 17 | 0.465 |
| Female | 31 (45.6%) | 16 | 15 | 14 | 17 | ||
| Size (cm) | |||||||
| ≥ 3 (cm) | 36 (52.9%) | 23 | 13 | 0.015* | 12 | 24 | 0.004* |
| < 3 (cm) | 32 (47.1%) | 11 | 21 | 22 | 10 | ||
| Stages | |||||||
| I/II | 30 (44.1%) | 14 | 16 | 0.625 | 18 | 12 | 0.143 |
| III/IV | 38 (55.9%) | 20 | 18 | 16 | 22 | ||
| T grade | |||||||
| T1 + T2 | 38 (55.9%) | 17 | 21 | 0.329 | 20 | 18 | 0.625 |
| T3 + T4 | 30 (44.1%) | 17 | 13 | 14 | 16 | ||
| Lymph node metastasis | |||||||
| N1–N3 | 40 (58.8%) | 22 | 18 | 0.324 | 17 | 23 | 0.139 |
| N0 | 28 (41.1%) | 12 | 16 | 17 | 11 | ||
| Lauren classification | |||||||
| Intestinal type | 30 (44.1%) | 12 | 18 | 0.330 | 19 | 11 | 0.094 |
| Diffuse type | 27 (39.7%) | 16 | 11 | 12 | 15 | ||
| Mixed type | 11 (16.2%) | 6 | 5 | 3 | 8 | ||
*P < 0.05 statistically significant difference