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. Author manuscript; available in PMC: 2018 May 27.
Published in final edited form as: ACS Infect Dis. 2017 Feb 17;3(3):206–215. doi: 10.1021/acsinfecdis.6b00176

Table 3.

Inhibition of Bacterial Growth (%) by Compounds 1–12 and Commercial Aminoglycosides at 6.3 µMa

compound E. coli E. faecalis K. pneumoniae P. mirabilis MRSA 33591 MRSA A960649 A. baumannii
1 7 11 0 0 7 2 0
2 84 39 0 87 6 3 0
3 53 3 0 14 6 3 0
4 73 ND 0 80 15 2 ND
5 74 11 0 80 15 0 0
6 87 29 0 52 0 12 0
7 71 0 2 23 7 3 0
8 67 46 0 31 0 1 0
9 38 9 0 2 5 0 0
10 62 0 0 4 2 0 0
11 36 12 0 12 ± 5 2 0 0
12 52 28 0 8 0 2 0
AMA 2 27 0 19 0 0 0
NEO 100 39 0 96 0 0 91
compound C. freundii E. cloacae L. monocytogenes P. aeruginosa S. epidermidis S. flexneri S. marcescens
1 54 ± 11 24 100 10 98 0 0
2 97 100 100 19 97 43 81 ± 11
3 65 ± 9 27 100 9 100 16 0
4 ND ND ND ND ND ND ND
5 97 76 100 16 100 78 93
6 95 52 100 18 100 48 ± 6 0
7 86 28 100 0 100 23 ± 6 0
8 96 54 100 16 100 54 ± 10 67
9 96 33 100 0 100 53 ± 6 8
10 96 27 100 0 100 67 18 ± 6
11 94 18 100 16 100 36 ± 5 63
12 95 38 ± 8 100 4 100 38 ± 7 68 ± 5
AMA 4 0 37 5 0 9 0
NEO 97 100 100 11 95 100 100
a

Standard error (±) is given for replicate assays when the error was >5%.