Table 4.
Laplace regression models (with years gained or lost until first 25% of incident diagnosis of CHF, and 95% confidence interval) among patients aged ≥45 years with diagnoses of atrial fibrillation (n=9,424) in primary care attending the 75 primary health care centers between January 1st 2001 and December 31st 2007; patients with a known hospital episode of congestive heart failure excluded
| Men | Women | |||||
|---|---|---|---|---|---|---|
| Age-adjusted | Adjusted for age and socio-demography | Fully adjusted | Age-adjusted | Adjusted for age and socio-demography | Fully adjusted | |
| Diagnosis | ||||||
| Hypertension | −0.24 (−0.59; 0.11) | −0.47 (−0.92; −0.01) | −0.30 (−0.74; 0.13) | 0.66 (0.03; 1.30) | 0.78 (0.28; 1.28) | 0.80 (0.26; 1.35) |
| Myocardial infarction | −0.52 (−1.68; 0.64) | −0.55 (−1.27; 0.17) | - | 0.00 (−1.24; 1.24) | −0.22 (−1.25; 0.80) | - |
| Valvular heart disease | −2.00 (−2.54; −1.46) | −2.41 (−3.29; −1.52) | −2.45 (−3.52; −1.38) | −2.00 (−2.72; −1.28) | −2.06 (−2.78; −1.35) | −1.99 (−3.08; −0.91) |
| Cardiomyopathy | −5.43 (−8.19; −2.67) | −6.99 (−8.60; −5.38) | −5.78 (−7.15; −4.41) | −2.99 (−5.10; −0.88) | −2.42 (−9.88; 5.03) | −2.12 (−3.99; −0.26) |
| Cerebrovascular diseases | 0.00 | - | - | 0.00 | - | - |
| Diabetes mellitus | −1.34 (−2.15; −0.54) | −1.45 (−1.97; −0.94) | −1.47 (−2.05; −0.91) | −1.12 (−1.53; −0.71) | −1.13 (−1.73; −0.53) | −1.16 (−1.85; −0.46) |
| Obesity | −1.03 (−1.85; −0.21) | −1.14 (−2.33; 0.05) | - | −1.24 (−3.10; 0.62) | −1.22 (−2.95; 0.51) | - |
| COPD | −1.72 (−2.34; −1.11) | −1.66 (−2.47; −0.86) | −1.53 (−2.14; −0.91) | −1.93 (−2.55; −1.32) | −2.00 (−2.72; −1.28) | −1.76 (−2.45; −1.07) |
| Obstructive sleep apnea syndrome | −2.61 (−4.69; −0.53) | −3.13 (−4.79; −1.48) | −2.11 (−3.92; −0.31) | −1.99 (−3.03; −0.96) | −1.46 (−3.49; 0.57) | −2.68 (−4.78; −0.58) |
| Depression | −0.14 (−0.76; 0.48) | −0.27 (−1.27; 0.73) | - | −0.20 (−0.87; 0.46) | −0.36 (−0.97; 0.26) | - |
| Anxiety | −0.64 (−2.13; 0.86) | −0.68 (−1.85; 0.48) | - | −0.63 (−1.87; 0.61) | −0.34 (−1.11; 0.43) | - |
Models are harmonized to include the same variables among men and women, otherwise are non-significant variables excluded. Fully adjusted includes adjustment forage, socio-demographic and all significant co-morbidity(hypertension, valvular heart disease, cardiomyopathy, diabetes, COPD, and obstructive sleep apnea syndrome) in models adjusted for age and socio-demographic factors (educational level, marital status, and neighborhood socio-economic status). (Model check did not reveal any significant interactions in full models).
COPD, chronic obstructive pulmonary disease.