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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: J Nutr Biochem. 2018 Feb 2;56:65–73. doi: 10.1016/j.jnutbio.2018.01.011

Figure 4. The VDR is necessary for Abx-induced production of 24,25D.

Figure 4

A) Vitamin D, B) 25D and C) 24,25D levels from serum of WT and VDR KO mice. Values are the mean ± SEM of n=11–14 mice per group, 15 males and 10 females, and 2 pooled independent experiments. D) 24,25D levels from serum of WT and Rag KO. Values are the mean ± SEM of n=5 mice per group, 4 males and 6 females. E) 24,25D levels from serum of WT/WT and WT/VDR KO. Values are the mean ± SEM of n=4 recipient male mice per group. 2-way ANOVA with Bonferroni post-hoc test was used to test significance. *P<0.05, **P<0.01, ***P<0.001