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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Virology. 2018 Apr 30;519:131–144. doi: 10.1016/j.virol.2018.04.012

Figure 6.

Figure 6

Comparison of IFN-I response and IRF4 expression between LCMV- and VACV-induced splenic NK cells. A. Serum IFN-I titers. B. Average IFNAR1 expression on all NK cells present in naïve, LCMV-, and VACV-infected mice. C. Overlaid flow cytometry profiles showing IRF4 protein expression in NK cells from representative naive and infected mice (each histogram represents NK cells from a single mouse). D, E. IRF4 prevalence and expression levels in NK cells. F-I. Correlation of IRF4 prevalence and expression levels to GzmB and CD69. J, K. Correlation of IRF4 prevalence and expression level to NKG2A. * p < 0.05, ** p < 0.02, *** p < 0.01. NK cell gating scheme: Singlets (FSC)>Lymphocytes(SSC)>NK 1.1(+) CD3(-).