Keratinocytes containing either episomal (a,b) or integrated (c) HPV16 genomes were grown in either monolayer (Mono) or in 1.6% methylcellulose (MC) culture medium containing either 33 ng/ml HGF (a,c) or 10 μM SU11274 (b,c) for 24 hours. Total RNA was isolated and levels of early (E6-7) or late (E1^E4) transcripts were measured by RT-qPCR. *=p<0.05, **=p<0.01, ***p<0.001.