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Summary of the newly predicted anticancer indications of natural products using the experimentally validated DTIs (ExpNet) only and the combination of the experimentally validated and network-based predicted DTIs (ExpNet&ComNet) respectively.
| Data source | # of DTIs (# targets, # drugs) | # SDCs (#drugs) (q<0.05) | # SDCs (# drugs) (q<1/10−5) |
|---|---|---|---|
| ExpNet | 1,479(409,163) | 635 (124) | 254 (66) |
| ExpNet&ComNet | 2,882 (525, 275) | 993 (196) | 519 (141) |
SDCs denote to significant drug-cancer indication pairs
