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Cre recombination and Myc overexpression in the eye. A and B: Nestin-Cre recombination in the eye of an 8-week–old (wko) mouse, shown by red-to-green transition in the RosamTmG mouse strain. The boxed area in A is enlarged in B to show the ciliary body of the eye. C: Myc-positive stained nuclei in tumorigenic regions of ciliary body of the eye in Myc-overexpressed (OE) mice. Scale bars: 100 μm (A); 50 μm (B); 20 μm (C). WT, wild-type.
