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. 2018 May 10;2018:1239143. doi: 10.1155/2018/1239143

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Copyright © 2018 Haowen Qiao et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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NADPH oxidase pathway mediates hBM-MSC inhibition of HSC activation. The cocultures and activated HSCs were harvested after being cultured for 24, 48, and 72 hours. (a) NADPH oxidase activity was measured. (b) p47phox mRNA level relative to cyclophilin was analyzed by real-time PCR (n = 3). ^∗P < 0.05 versus the control group. (c, d) NOX2, p47phox, and p-p47phox were evaluated by Western blot. Experiments were performed in triplicate. ^∗P < 0.05 versus the control group and ^∗∗P < 0.001 versus the control group.