Table 2.
Genotype and allele frequency of SNPs rs3752462 and rs136161 between DKD patients (n = 303) and DM controls (n = 364).
| Genotypes, n (%) | Alleles, n (%) | |||||||
|---|---|---|---|---|---|---|---|---|
| rs3752462 | TT | TC | CC | HWE P value | P | T | C | P |
| DM | 227 (62.4%) | 115 (31.6%) | 22 (6.0%) | 0.155 | 0.004∗ | 569 (57.1%) | 159 (42.9%) | 0.002 ∗ ,∆ |
| DKD | 150 (49.5%) | 128 (42.2%) | 25 (8.3%) | 0.752 | 428 (70.6%) | 178 (29.4%) | ||
| rs136161 | CC | CG | GG | HWE P value | P | C | G | P |
| DM | 213 (58.5%) | 126 (34.6%) | 25 (6.9%) | 0.287 | 0.944 | 552 (75.8%) | 176 (24.2%) | 0.751 |
| DKD | 180 (59.4%) | 104 (34.3%) | 19 (6.3%) | 0.449 | 464 (76.6%) | 142 (23.4%) | ||
∗ P < 0.05; ∆ indicates statistical significance by Holm-Bonferroni correction; HWE: Hardy-Weinberg equilibrium.