Table 3.

GEE analyses demonstrating the association between vision-related QoL (per 5 points) and pRNFL and GCIPL thickness.

	pRNFL β (95% CI)	p value	GCIPL β (95% CI)	p value
Vision-related QoL (unadjusted)	1.03 (0.01 to 2.01)	0.038	1.12 (0.26 to 1.99)	0.011
Vision-related QoL (adjusted for age, sex, and use of DMT)	0.96 (0.01 to 1.91)	0.048	1.08 (0.28 to 1.87)	0.008
Vision-related QoL (adjusted for age, sex, use of DMT, and MSON	0.92 (−0.04 to 1.87)	0.060	0.93 (0.15 to 1.71)	0.020

CI: confidence interval; GEE: generalized estimating equations; pRNFL: peripapillary retinal nerve fiber layer; GCIPL: ganglion cell inner plexiform layer; QoL: quality of life; MSON: MS-associated optic neuritis; DMT: disease-modifying treatment.

Adjustments for age, sex, use of DMT, and history of MSON had minimal effect. Data shown as β (95% CI, p value).

All analyses were corrected for inter-eye dependency.