Table 4.
The frequency of the UGTA1 rs8175347 genotypes among the three Chinese ethnic groups stratified according to hepatitis B virus (HBV) infection status.
| Ethnic groups | Genotype | HBV infected | HBV uninfected | Statistical significance | Odds ratio (95% CI) | |
|---|---|---|---|---|---|---|
| Yi* | n = 53 | n = 48 | χ2= 4.974aNS | |||
| 431 bp (6TA) | 21 (19.8) | 12 (12.5) | χ2 = 1.970bNS | 1.585 (0.825, 3.046) | ||
| 433 bp (7TA) | 83 (78.3) | 77 (80.2) | χ2 = 0.111bNS | |||
| 435 bp (8TA) | 2 (1.9) | 7 (7.3) | χ2 = 3.457bNS | χ2 = 16.7cP < 0.001 | ||
| Yao | n = 80 | n = 58 | χ2 = 4.626aNS | |||
| 431 bp (6TA) | 11 (6.9) | 17 (14.7) | χ2 = 4.465bP < 0.05 | |||
| 433 bp (7TA) | 138 (86.3) | 93 (80.2) | χ2 = 1.820bNS | 1.215 (0.463, 3.185) | ||
| 435 bp (8TA) | 11 (6.9) | 6 (5.2) | χ2 = 0.337bNS | |||
| Han | n = 130 | n = 35 | χ2 = 1.597aNS | |||
| 431 bp (6TA) | 18 (6.9) | 8 (11.4) | χ2 = 1.542bNS | |||
| 433 bp (7TA) | 212 (81.5) | 55 (78.6) | χ2 = 0.314bNS | 1.038 (0.906, 1.188) | ||
| 435 bp (8TA) | 30 (11.5) | 7 (10.0) | χ2 = 0.131bNS | |||
Data presented as n of genes (%).
aP-value from χ2-test with two degrees of freedom.
bP-value from χ2-test with one degree of freedom.
cP-value from χ2-test in the same genotype between Yi and Yao groups with two degrees of freedom.
*P < 0.01, significant difference in the frequency of 8TA between the Yi and Yao groups; χ2-test.
CI, confidence interval; bp, base pairs; NS, no significant difference (P ≥ 0.05).