Table 5.
The frequency of the UGT1A6 rs2070959 genotypes among the three Chinese ethnic groups stratified according to hepatitis B virus (HBV) infection status.
| Ethnic groups | Genotype | HBV infected | HBV uninfected | Statistical significance | Odds ratio (95% CI) | |
|---|---|---|---|---|---|---|
| Yi* | n = 53 | n = 48 | χ2 = 2.764aNS | |||
| GG | 1 (1.9) | 3 (6.3) | χ2 = 1.261bNS | |||
| AG | 19 (35.8) | 22 (45.8) | χ2 = 1.041bNS | |||
| AA | 33 (62.3) | 23 (47.9） | χ2=2.099bNS | χ2 = 6.232cP < 0.05 | 1.793 (0.811, 3.964) | |
| Yao | n = 80 | n = 58 | χ2 = 1.027aNS | |||
| GG | 11 (13.8) | 6 (10.3) | χ2 = 0.361bNS | |||
| AG | 32 (40.0) | 28 (48.3) | χ2 = 0.927bNS | |||
| AA | 37 (46.3) | 24 (41.4) | χ2 = 0.323bNS | 1.219 (0.616, 2.143) | ||
| Han# | n = 130 | n = 35 | χ2 = 3.194aNS | |||
| GG | 21 (16.2) | 4 (11.4) | χ2 = 1.441bNS | χ2 = 8.67dP < 0.01 | ||
| AG | 42 (32.3) | 17 (48.6) | χ2 = 3.175bP NS | |||
| AA | 67 (51.5) | 14 (40.0) | χ2 = 1.469bNS | 1.595 (0.747, 3.407) | ||
Data presented as n of subjects (%).
aP-value from χ2-test with two degrees of freedom.
bP-value from χ2-test with one degree of freedom.
cP-value from χ2-test in the same genotype between Yi and Yao groups with two degrees of freedom.
dP-value from χ2-test in the same genotype between Han and Yi groups with two degrees of freedom.
*P < 0.05, significant difference between the Yi and Yao groups; χ2-test.
#P < 0.05, significant difference between the Han and Yi groups; χ2-test.
CI, confidence interval; NS, no significant difference (P ≥ 0.05).