TABLE 1.
Accuracy of identification of mycobacteriaa
| Reference identification | No. (%) of isolates with indicated Vitek MS v3.0 ID result |
|||
|---|---|---|---|---|
| Correct to species level | Correct to complex or group level | Incorrect | No ID | |
| M. tuberculosis complex (n = 45) (includes but does not discriminate among M. africanum, M. bovis/BCG, M. canettii, M. microti, M. pinnipedii, and M. tuberculosis | 45 (100) | |||
| NTM slow growers | ||||
| M. avium complex | ||||
| M. avium (n = 68) | 68 (100) | |||
| M. intracellulare (n = 43) | 42 (98) | 1 (2) | ||
| M. chimaeraN (n = 16) | 16 (100) | |||
| MAC-XN (n = 20) (includes but may not discriminate among M. arosiense, M. bouchedurhonense, M. colombiense, M. marseillense, M. timonense, M. vulneris, and M. yongonense) | 14 (70) | 6 (30) | ||
| M. simiae complex | ||||
| M. simiae (n = 28) | 28 (100) | |||
| M. lentiflavum (n = 37) | 33 (89) | 4 (10) | ||
| M. shigaenseN (n = 3) | 3 (100) | |||
| M. gordonae (n = 30) | 28 (93) | 2 (7) | ||
| M. gordonae/paragordonaeN (n = 3) | 1 (33) | 1 (33) | 1 (33) | |
| M. haemophilum (n = 18) | 17 (94) | 1 (6) | ||
| M. kansasii (n = 31) | 31 (100) | |||
| M. malmoense (n = 4) | 4 (100) | |||
| M. marinum (n = 25) | 25 (100) | |||
| M. nebraskense* (n = 1) | 1 (100) | |||
| M. paraenseN (n = 1) | 1 (100) | |||
| M. parascrofulaceumN (n = 2) | 1 (50) | 1 (50) | ||
| M. paraffinicumN (n = 9) | 2 (22) | 7 (78) | ||
| M. scrofulaceum (n = 15) | 15 (100) | |||
| M. szulgai (n = 24) Does not discriminate from M. angelicumb | 23 (96) | 1 (4) | ||
| M. xenopi (n = 24) | 24 (100) | |||
| Total (n = 402) | 339 (84) | 32 (8) | 4 (1) | 27 (7) |
| NTM rapid growers | ||||
| M. chelonae/abscessus group | ||||
| M. abscessus complex (n = 40); includes but does not differentiate subspecies abscessus, massiliense, and bolletii | 40 (100) | |||
| M. chelonaec (n = 29) | 28 (97) | 1 (3) | ||
| M. immunogenum (n = 19) | 19 (100) | |||
| M. fortuitum-smegmatis-farcinogenes group | ||||
| M. fortuitum group (n = 49); includes but does not discriminate between M. alvei, M. brisbanense, M. boenickei, M. farcinogenes,d M. fortuitum, M. houstonense, M. neworleansense, M. peregrinum, M. porcinum, M. senegalense, M. septicum, M. setense | 48 (98) | 1 (2) | ||
| M. smegmatise (n = 21) | 21 (100) | |||
| M. mageritense* (n = 1)f | 1 (100) | |||
| M. mucogenicum group | ||||
| M. mucogenicum (n = 20)g | 18 (90) | 2 (10) | ||
| M. phocaicumN (n = 21) | 20 (95) | 1 (5) | ||
| M. mucogenicum/phocaicumh (n = 1) | 1 (100) | |||
| M. neoaurum* (n = 1) | 1 (100) | |||
| Total (n = 202) | 88 (44) | 109 (54) | 5 (2) | |
| Mycobacterium species (n = 2) | 1 (50) | 1 (50) | ||
| Total (n = 651) | 427 (66) | 187 (29) | 4 (<1) | 33 (5) |
ID, identification; N, species not included in v3.0 database; *, organism included in v3.0 database but not included in FDA claim.
M. angelicum has the same first 500-bp rRNA gene sequence as M. szulgai; M. angelicum was not recognized in the gene sequence database at the time of the study. However, following the study period, all isolates were subjected to rpoB gene sequence analysis, which is required to differentiate the species from M. szulgai, and no isolates were identified as M. angelicum.
Other members of the M. chelonae complex, M. salmoniphilum, M. franklinii, and M. saopaulense, were not tested.
M. farcinogenes is a slowly growing Mycobacterium species.
The other member of the M. smegmatis group, M. goodii, was not tested.
The other closely related member, M. wolinskyi, was not tested.
The other member of the M. mucogenicum group, M. aubagnense, was not tested.
Most closely related.