TABLE 2.

Factors associated with having one or more PPCs of ≤0.7 mg/liter in the logistic regression model

Factor	Univariate analysis			Multivariate analysisa
	OR	95% CI	P valueb	OR	95% CI	P value
Age (per year)	0.98	0.95–1.02	0.335
Female sex	0.35	0.12–1.02	0.055	0.28	0.08–1.01	0.052
Allogeneic stem cell transplantation	1.47	0.47–4.64	0.508
GVHDc	3.92	1.30–11.84	0.016	7.00	1.67–29.42	0.008
Concomitant PPI	0.76	0.25–2.31	0.634
Diarrhea	1.51	0.44–5.24	0.514
Posaconazole DRT	0.15	0.04–0.58	0.005	0.07	0.01–0.39	0.002

^aHosmer-Lemeshow goodness-of-fit chi-square value, 5.284 (P = 0.382); ROC area under the curve of the model, 0.84 (95% CI, 0.74 to 0.94).

^bP values of <0.2, the cutoff for inclusion of the respective variables in the multivariable model, are in bold.

^cSixty percent of patients receiving DRT and 40% of patients receiving OS had GVHD grade 3 or 4; the rest had GVHD grade 1 or 2.