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Week 1 percent probabilities of PK-PD target attainment by MIC based on the free-drug AUC0–168/MIC ratio targets associated with net fungal stasis and 1-log10 CFU reductions from baseline for C. albicans (gray solid and dashed lines, respectively) and C. glabrata (burgundy solid and dashed lines, respectively) among simulated patients administered 400 mg of rezafungin overlaid upon worldwide C. albicans and C. glabrata MIC distributions.
