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Distributions of free-drug AUC0–168/MIC ratios at the MIC90 value for C. albicans of 0.06 mg/liter for simulated patients administered the single-dose and weekly rezafungin regimens shown relative to the free-drug AUC0–168/MIC ratio targets associated with net fungal stasis and a 1-log10 CFU reduction from baseline. Plot whiskers represent the 5th and 95th percentiles of the AUC0–168/MIC ratios.
