TABLE 1.

For C. albicans, percent probabilities of PK-PD target attainment by MIC and for simulated patients randomly assigned MIC values based on nonclinical AUC_0–168/MIC ratio targets associated with net fungal stasis and a 1-log₁₀ CFU reduction from baseline following administration of single-dose and weekly rezafungin regimens

^a Shaded cells indicate percent probabilities of PK-PD target attainment of ≥90%.

^b Simulated patients were randomly assigned MIC values based on the C. albicans in vitro surveillance data presented in Table 3.