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Bayesian parameter estimates for kill rates for both sensitive and resistant populationsa
| Dosing regimen | Kkill-s (h−1) | Kkill-r (h−1) |
|---|---|---|
| 12 g q24h | 2.315 | 1.652 |
| 4 g q8h | 2.007 | 1.803 |
| 12 g CI | 1.991 | 3.290 |
| 18 g q24h | 2.406 | 1.690 |
| 6 g q8h | 2.322 | 1.831 |
| 18 g CI | 2.147 | 2.019 |
Kkill-s and Kkill-r, maximal first-order kill rate constants for the susceptible and resistant bacterial populations, respectively; q24h, every 24 h; q8h, every 8 h; CI, continuous infusion.
