TABLE 3.

Mean ∑FICs of the interaction between ravuconazole and benznidazole toward intracellular amastigotes of the Y and Colombian Trypanosoma cruzi strains^a

Bz/Rav ratio	Y strain			Colombian strain
	Bz FIC	Rav FIC	∑FIC	Bz FIC	Rav FIC	∑FIC
4:1	0.64 ± 0.004	0.12 ± 0.12	0.76	0.76 ± 0.19	0.34 ± 0.15	1.10
3:2	0.58 ± 0.26	0.25 ± 0.15	0.83	0.75 ± 0.04	0.81 ± 0.37	1.56
2:3	0.42 ± 0.16	0.44 ± 0.30	0.86	0.42 ± 0.25	1.05 ± 0.09	1.45
1:4	0.26 ± 0.18	0.72 ± 0.035	0.98	0.15 ± 0.07	1.01 ± 0.26	1.16
Mean FIC in combination	0.47 ± 0.15	0.39 ± 0.15	0.86	0.52 ± 0.29	0.79 ± 0.32	1.31

^aFICs, fractional inhibitory concentrations at the IC₅₀ level; Bz, benznidazole; Rav, ravuconazole.