TABLE 1.
IC50s of DS-2969b and levofloxacin for S. aureus and human topoisomerases
| Compound | IC50 (μg/ml) |
||
|---|---|---|---|
|
S. aureus |
Human topoisomerase II | ||
| DNA gyrase | Topoisomerase IV | ||
| DS-2969b | 0.14 | 0.84 | >200 |
| Levofloxacin | 52 | 6.5 | >1,024 |
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