Table 1.
The clinical characteristics of the subjects included in the study
| Parameters | Uncontrolled asthma | Healthy control |
|---|---|---|
| Age (years) | 51.9(14.3) | 51.5(14.5) |
| Male number (female) | 102(144) | 28(22) |
| Asthma duration (Years) | 2.5(0.15–40) | None |
| ACT scores | 15.6(2.57) | None |
| Allergic rhinitis | 55.28%(136/246) | None |
| Blood neutrophil counts (×109/L) | 4.05(1.81–13.7) | 3.67(2.75–5.48) |
| Blood neutrophil percentage (%) | 61.00(40.1–90.9 | 63.2(53.9–72) |
| Blood eosinophil counts (×109/L) | 0.15(0.01–6.95) | 0.1(0.04–0.17)** |
| Blood eosinophil percentage (%) | 2.4(0.2–47.2) | 1.5(0.6–3.2)* |
| IgE (IU/ml)(<165) | 41.2(5–2662) | |
| Pre-FEV1/FVC | 76.75(15.33) | 84.92(5.58)* |
| Post-FEV1/FVC | 77.00(15.30) | 85.85(5.60) * |
| Pre-FEV1(L) | 2.39(0.97) | 2.8(0.75) * |
| Post-FEV1(L) | 2.52(0.96) | 2.98(0.72) * |
| Pre-FEV1% predictated | 91.53(29.29) | 110.47(18.64) ** |
| Post-FEV1%% predictated | 97.52(28.69) | 117.76(16.55) ** |
| Pre-FEF25–75% predictated | 72.53(39.35) | 98.19(22.48) ** |
| Post-FEF25–75% predictated | 78.09(39.07) | 109.76(24.63) ** |
| Pre-FEF50% predictated | 75.33(42.32) | 103.69(25.53) ** |
| Post-FEF50% predictated | 83.00(42.46) | 117.76(27.22) ** |
| FENO(ppb) | 22(5–300) | 17(8–26) * |
| SOD(U/ml) | 157.73(22.98) | 206.75(21.26) * |
Note:
*
P<0.05 vs control group,
**
P<0.01 vs control group,
Abbreviations: ACT scores, asthma control test scores; FEV1, forced expiratory volume in one second; FVC, forced vital capacity; FEF, forced expiratory flow; FENO, fractional exhaled nitric oxide.