Fig 6.
Bar graphs for the neurochemicals that showed significant changes between the 5xFAD and 5xFAD +7,8-DHF animals. Left - Changes in the choline-containing chemicals glycerolphosphocholine (GPC), phosphocholine (PhC) and choline (Cho). 7,8-DHF treatment normalized the increases noted in PhC and Cho. Right – Glutamate levels in the hippocampus of WT, 5xFAD and 5xFAD+7,8-DHF treated mice showing the treatment effects of the DHF. **P<0.01 or * P < 0.05 for differences of the mean compared to the 5xFAD animals.