Table 1. Risk factors analysis for early-onset ventilator-acquired pneumonia (EOVAP) in patients with aneurysmal subarachnoid hemorrhage (SAH).
| Patients without EOVAP (n=120) | Patients with EOVAP (n=80) | P value | |
|---|---|---|---|
| Characteristics SAPS II | 41±14 | 42±13 | 0.82 |
| Age | 53±13 | 54±13 | 0.76 |
| Gender (male) | 36 (30) | 36 (45) | 0.04 |
| GCS score | 9±4 | 9±5 | 0.66 |
| WFNS ≥III | 88 (59.4) | 60 (75) | 0.79 |
| Active smoking | 17 (14.2) | 20 (25) | 0.08 |
| Seizures before intubation | 29 (24.2) | 30 (37.5) | 0.04 |
| Aneurysmal coiling | 104 (86.6) | 64 (80) | 0.29 |
| Ventriculostomy | 77 (64.2) | 44 (55) | 0.19 |
| Antibioprophylaxis | 27 (22.5) | 23 (28.8) | 0.32 |
| Angiographic vasospasm before day 7 | 11 (9.2) | 12 (15) | 0.21 |
| Enteral nimodipine | 40 (33.3) | 29 (36.3) | 0.78 |
| Insulin therapy | 92 (76.7) | 62(77.5) | 0.89 |
| Stress ulcer prophylaxis | 114 (95) | 76 (95.0) | 0.74 |
| Use of mannitol | 32 (26.7) | 42 (52.5) | 0.0003 |
| Corticosteroids | 6 (5) | 4 (5) | 0.74 |
| Barbiturates use (days) | 3±2 | 4±3 | 0.47 |
| Achievement of enteral feeding ≥20 kcal·kg−1·day−1before day 7 | 71 (59.2) | 64 (80) | 0.003 |
Data are reported as means±SD or number and percentage. SAPS: Simplified Acute Physiology Score; GCS: Glasgow coma scale; WFNS: World Federation of Neurosurgeons score. The χ2 or Fisher's exact test was employed for qualitative variables, and Student's t-test or the Wilcoxon non-parametric test was used for quantitative variables.