Table 4. Hazard ratios and 95% confidence intervals for the association between creatinine-adjusted urinary cadmium level and risk of hypertension n = 2865.
Incident Cases/N | Unadjusted | Model 1 | Model 2 | |
---|---|---|---|---|
Continuous | 626/2865 | 1.02 (0.95–1.10) | 1.09 (1.01–1.19) | 1.10 (1.01–1.20) |
First quintile | 114/564 | 1.00 (Ref) | 1.00 (Ref) | 1.00 (Ref) |
Second quintile | 132/582 | 0.99 (0.85–1.15) | 1.03 (0.89–1.21) | 1.04 (0.89–1.22) |
Third quintile | 141/583 | 0.94 (0.81–1.10) | 1.02 (0.87–1.20) | 1.04 (0.89–1.23) |
Fourth quintile | 106/580 | 1.03 (0.88–1.21) | 1.12 (0.95–1.32) | 1.15 (0.97–1.36) |
Fifth quintile | 133/556 | 1.02 (0.87–1.20) | 1.15 (0.97–1.37) | 1.17 (0.97–1.40) |
Model 1: Sex, age, and center.
Model 2: Model 1 + estimated glomerular filtration rate, body mass index, education level, alcohol consumption, diabetes status, triglycerides, total cholesterol, high-density lipoprotein cholesterol, physical activity level. 182 individuals excluded due to missing covariates.