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. Author manuscript; available in PMC: 2019 Jun 10.
Published in final edited form as: J Control Release. 2018 Apr 11;279:114–125. doi: 10.1016/j.jconrel.2018.04.014

Figure 2.

Figure 2

LPV concentrations from LPV-polymer ASDs at pH 3 after A) 3h and B) 48h. dash line: ideal behavior. The amorphous solubility of lopinavir (17.4μg/mL) is used for the 100% drug loading point. 20 μg/mL of HPMC was added to the buffer to inhibit solution crystallization of lopinavir, thereby enabling the maximum release of LPV from the various amorphous solid dispersions to be directly compared.