Table 2.
Diagnostic performance of S-detect and in-training operators
| Operator | Sensitivity (%)—95% CI | Specificity (%)—95% CI | PLR—95% CI | NLR—95% CI | ROC area—95% CI | PPV (%)—95% CI | NPV (%)—95% CI |
|---|---|---|---|---|---|---|---|
| S-detect | 91.1 (78.8–97.5%) | 70.8 (48.9–87.4%) | 3.12 (1.66 5.87) | 0.13 (0.05–0.33) | 0.81(0.71–0.91) | 8.54 (72.2–93.9%) | 81.0 (58.1–94.6%) |
| 5th year with limited experiencea | 97.7% (88–99.9%) | 54.2 (32.8–74.4%) | 2.13 (1.38–3.30) | 0.04 (0.01–0.30) | 0.76 (0.66 –0.86) | 79.6 (66.5–89.4) | 92.9 (66.1–99.8%) |
| 2nd year with deeper experiencea | 95.5 (84.5–99.4%) | 70.8 (48.9–87.4%) | 3.27 (1.75–6.13) | 0.06 (0.02–0.25) | 0.83 (0.73–0.93) | 85.7 (72.8–94.1) | 89.5 (66.9–98.7) |
| 3rd year with limited experiencea | 97.8 (88.2–99.9) | 50 (29.1–70.9%) | 1.96 (1.31–2.92) | 0.04 (0.01–0.32) | 0.74 (0.63–0.84) | 78.6 (65.6–88.4%) | 92.3 (64–99.8%) |
| 1 anno with deeper experiencea | 100 (92–100%) | 50 (29.1–70.9%) | 2.0 (1.34–2.98) | 0.00 | 0.75 (0.65–0.85) | 78.6 (65.6–88.4%) | 100 (73.5–100%) |
PLR positive likelihood ratio, NLR negative likelihood ratio, ROC receiver operator curve, PPV positive predictive value, NPV negative predictive value
aExperience in breast imaging