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. 2018 May 22;11:166. doi: 10.3389/fnmol.2018.00166

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Copyright © 2018 Veszelka, Tóth, Walter, Tóth, Gróf, Mészáros, Bocsik, Hellinger, Vastag, Rákhely and Deli.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of the expression of selected BBB genes between the primary rat brain endothelial cell-based EPA model and the human brain endothelial cell line D3 (A), and the human intestinal cell line Caco-2 (B) measured by inventoried TaqMan Gene Expression Assays. The figure shows the ratio between the gene expression level of tight junction proteins (TJ, red square), influx transporters (IT, blue dot), efflux transporters (ET, green triangle) and selected metabolic enzymes (ME, yellow diamond) in EPA and D3 or Caco-2 cells. The graph also displays the expression values in the EPA sample on the y-axis to demonstrate the level of expression of studied genes.