Table 2. Protein Levels of TIMP3 in BRAF V600E and Lymph Node Metastasisa.
Variable | Tissues Status | Lymph Node Metastasis Status | |||||
---|---|---|---|---|---|---|---|
All PTCs | No | Yes | |||||
No | Yes | BRAF (-) | BRAF (+) | BRAF (-) | BRAF (+) | ||
TIMP3 protein level, ng/mL | Tumoral | 7.17 ± 3.02 | 7.55 ± 2.63 | 7.47 ± 3.16 | 6.87 ± 3.04 | 8.08 ± 3.39 | 7.08 ± 1.74 |
Matched non-tumoral | 9.09 ± 3.35 | 12.4 ± 6.78 | 7.58 ± 2.55 | 10.6 ± 3.49 | 12.5 ± 6.84 | 12.2 ± 7.10 | |
P value | 0.086 | 0.004b | 0.939 | 0.028b | 0.043b | 0.048b |
Abbreviations: TIMP3, tissue inhibitor of metalloproteinase-3; PTC, papillary thyroid carcinoma.
a Data are presented as Mean ± SD
b P value < 0.05