Table 2.
Sex-adjusted analysis on correlation between serum MCP-1 concentration and clinical parameters in smokers.
| Univariate |
Multivariate |
|||
|---|---|---|---|---|
| β value | p value | β value | p value | |
| Age (years) | 0.311 | <0.001 | – | – |
| BMI (kg/m2) | −0.037 | 0.581 | – | – |
| Waist circumference (cm) | 0.050 | 0.528 | ||
| SBP (mmHg) | 0.225 | 0.001 | 0.167 | 0.028 |
| DBP (mmHg) | 0.137 | 0.045 | – | – |
| HbA1c (%) | −0.005 | 0.940 | – | – |
| eGFR (mL/min/1.73 m2) | −0.244 | 0.001 | – | – |
| HDL-C (mg/dL) | 0.065 | 0.386 | – | – |
| LDL-C (mg/dL) | −0.002 | 0.976 | – | – |
| hsCRP (mg/L) | −0.008 | 0.921 | ||
| Daily tobacco consumption (n) | −0.065 | 0.344 | – | – |
| Duration of smoking (years) | 0.342 | <0.001 | 0.307 | <0.001 |
| Brinkman index (pack-years) | 0.053 | 0.459 | – | – |
| CO (ppm) | −0.131 | 0.056 | – | – |
| FTND score | −0.119 | 0.080 | – | – |
| SDS score | −0.092 | 0.194 | – | – |
β value: correlation coefficient, R2 = 0.206
MCP-1, monocyte chemoattractant protein-1; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HbA1c, hemoglobin A1c; eGFR, estimated glomerular filtration rate; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; hsCRP, high-sensitivity C-reactive protein; CO, carbon monoxide; FTND, Fagerström Test for Nicotine Dependence; SDS, Zung Self-Rating Depression Scale.