Table 1.
Postmortem heart weight and body weight, in vivo echocardiographical measurements (fractional shortening, stroke volume, LVIDd, LV WTd, IVS WTd, and relative LV + IVS WTd), length, width, and length:width ratio of enzymatically isolated cardiomyocytes, lung weight, and deltoid citrate synthase activity of CON, AB, and AB-LIT groups
| CON | AB | AB-LIT | |
|---|---|---|---|
| Post mortem heart weight, g | 207.5 ± 9.8 | 256.3 ± 9.2* | 257.4 ± 7.0* |
| Post mortem body weight, kg | 46.1 ± 2.2 | 47.4 ± 2.4 | 47.7 ± 1.3 |
| In vivo fractional shortening | 46 ± 2 | 47 ± 2 | 47 ± 2 |
| In vivo stroke volume, ml | 67 ± 4 | 65 ± 3 | 62 ± 3 |
| LVIDd, mm | 49 ± 2 | 47 ± 1 | 50 ± 1 |
| LV WTd, mm | 7.4 ± 0.4 | 8.3 ± 0.7 | 8.2 ± 0.4 |
| IVS WTd, mm, | 11.0 ± 0.4 | 12.2 ± 0.2† | 11.8 ± 0.4 |
| Relative LV + IVS WTd | 0.38 ± 0.01 | 0.44 ± 0.02* | 0.40 ± 0.01# |
| Cardiomyocyte length, µm | 214 ± 4 | 207 ± 4 | 191 ± 3*# |
| Cardiomyocyte width, µm | 38 ± 1 | 43 ± 1* | 36 ± 1# |
| Length:width ratio | 6.0 ± 0.2 | 5.4 ± 0.2* | 5.6 ± 0.2* |
| Lung weight, g | 267 ± 14 | 317 ± 21† | 294 ± 10 |
| Deltoid citrate synthase activity, µmol·g wet weight−1·min−1 | 20.4 ± 2.8 | 15.2 ± 2.0 | 21.5 ± 4.3 |
CON, control; AB, aortic-banded; AB-LIT, aortic-banded exercise trained; LVIDd, left ventricular internal diastolic dimension; LV WTd, left ventricular diastolic wall thickness; IVS WTd, interventricular septum diastolic wall thickness; relative LV + IVS WTd, left ventricular and septal diastolic wall thickness normalized to LVIDd calculated as (LV WTd + IVS WTd)/LVIDd.
P < 0.05 vs. CON.
P < 0.05 vs. AB.
P < 0.10 vs. CON.