Table 1.

Engraftment of CD45.1⁺ donor cells into the BM, spleen, and lymph nodes of control-chimeric (C-chim) and dmPGE₂-chimeric (dmPGE₂-chim) mice

	Weeks reconstituted	BM			Spleen			Lymph nodes

		WT	C-chim	dmPGE₂-chim	WT	C-chim	dmPGE₂-chim	WT	C-chim	dmPGE₂-chim
Total cells (×10⁶)	4	60.4 ± 6.8	46.2 ± 6.2	49.6 ± 0.8	103.2 ± 4.0	64.4 ± 6.0	55.4 ± 1.0	-	-	-
	12	62.0 ± 11.8	50.5 ± 1.6	46.7 ± 4.7	74.5 ± 6.5	70.1 ± 5.4	80.4 ± 6.0	-	-	-
%CD19⁺B220⁺	12	23.1 ± 3.0	28.4 ± 1.8	27.6 ± 1.4	45.5 ± 3.5	49.8 ± 1.9	50.9 ± 1.7	32.7 ± 2.6	32.0 ± 2.8	30.5 ± 2.9
% CD45.1		0.05 ± 0.0	97.8 ± 0.6	98.4 ± 0.1	0.1 ± 0.0	99.7 ± 0.1	99.7 ± 0.1	0.1 ± 0.1	99.7 ± 0.1	99.6 ± 0.1
%CD3⁺CD4⁺	12	1.0 ± 0.2	1.0 ± 0.1	0.7 ± 0.1	11.6 ± 1.2	13.4 ± 2.0	9.9 ± 1.0	21.2 ± 4.8	33.4 ± 2.3	33.3 ± 2.2
% CD45.1		0.1 ± 0.0	84.9 ± 2.6	87.6 ± 3.2	0.1 ± 0.0	92.1 ± 1.1	88.9 ± 1.7	0.1 ± 0.0	95.1 ± 1.2	93.0 ± 0.9
%CD3⁺CD4^–	12	2.5 ± 0.7	2.9 ± 0.1	2.1 ± 0.2	12.1 ± 0.1	8.8 ± 0.8	7.4 ± 0.6	27.7 ± 6.6	29.5 ± 0.3	28.1 ± 0.8
% CD45.1		0.1 ± 0.0	88.7 ± 1.6	87.6 ± 0.8	0.0 ± 0.0	93.7 ± 0.2	90.6 ± 1.2	0.0 ± 0.0	95.7 ± 0.3	92.9 ± 0.6
%F4/80⁺CD11b⁺	12	8.9 ± 1.4	13.3 ± 0.9	14.5 ± 0.5	1.5 ± 0.1	2.9 ± 0.6	3.0 ± 0.3	1.2 ± 0.4	1.2 ± 0.5	0.6 ± 0.1
% CD45.1		1.5 ± 0.4	99.8 ± 0.0	99.8 ± 0.0	4.6 ± 0.6	99.1 ± 0.2	99.1 ± 0.2	3.5 ± 0.7	98.9 ± 0.5	99.7 ± 0.1
%CD11c⁺	12	2.5 ± 0.2	2.3 ± 0.1	2.2 ± 0.1	3.7 ± 0.0	3.7 ± 0.2	4.4 ± 0.5	3.9 ± 0.5	4.8 ± 0.0	3.9 ± 0.3
% CD45.1		5.5 ± 1.4	97.3 ± 0.8	98.1 ± 0.4	0.4 ± 0.2	97.0 ± 0.2	96.0 ± 0.0	0.4 ± 0.2	97.7 ± 0.3	96.5 ± 0.5

Comparison of cell yields and cell types from wild-type (WT, nonchimeric) mice are shown at 4 and 12 weeks after injection of cells. Data are shown as mean ± SEM for three individual mice.