Table 2.
Classification | Group | Number | Percentages in PB
|
Percentages in KM
|
Leukemic cell types | ||||
---|---|---|---|---|---|---|---|---|---|
Myelomonocytes | Lymphocytes | Precursors | Myelomonocytes | Lymphocytes | Precursors | ||||
Sibling | 14 | 18.5 ±2.6 | 68.0 ±5.3 | 14 ±3.9 | 45.0 ±2.7 | 32.8 ±2.0 | 22.3 ±1.7 | ||
c-mybhyper-MDS | 47 | 14.8 ±2.4 | 76.3 ±2.4 | 8.9 ±0.8 | 73.1 ±1.9 | 16.5 ±1.4 | 10.5 ±0.9 | Neutrophil | |
c-mybhyper-AML | I | 2 | 8.7 ±4.2 | 32.8 ±15.9 | 58.5 ±20.0a | 23.0 ±13.5 | 34.5 ±8.5 | 42.0 ±4.9a | Neutrophil |
II | 12 | 12.3 ±4.6 | 26.1 ±5.1 | 61.6 ±8.0a | 77.8 ±2.8 | 12.5 ±2.3 | 9.7 ±1.1 | Neutrophil | |
III | 4 | 15.5 ±1.5 | 74.2 ±1.4 | 10.3 ±2.8 | 36.7 ±1.5 | 22.2 ±1.0 | 41.1 ±0.6a | Neutrophil | |
c-mybhyper-ALL | I | 13 | 6.0 ±2.1 | 89.2 ±3.0b | 4.9 ±1.7 | 27.7 ±5.5 | 60.6 ±6.6b | 11.5 ±4.3 | T-cell |
II | 5 | 0.9 ±0.2 | 18.8 ±7.1 | 80.3 ±7.2c | 29.3 ±10.3 | 64.4 ±11.1b | 6.8 ±2.4 | B-cell |
The percentages were indicated by mean ±s.e.m. Adult c-mybhyper fish characterized by >25% precursors with myeloblasts morphology in PB or >40% in KM were divided into AML; and fish characterized by >80% lymphocytes or >60% precursors with lymphoblasts morphology in the PB, and >40% in the KM were divided into ALL. AML-Group I: precursors increased in both PB and KM. AML-Group II: precursors increased in PB. AML-Group III: precursors increased in KM. ALL-Group I: lymphocytes increased in both PB and KM. ALL-Group II: precursors increased in PB and lymphocytes increased in KM (mean ± s.e.m.).
Indicates precursors in PB or KM increased >25% or 40%, respectively, in AML.
Indicates lymphocytes in PB or KM increased >80% or >40%, respectively, in ALL.
Indicates precursors in PB increased >60% in ALL.