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. 2017 Nov 3;6(11):e17082. doi: 10.1038/lsa.2017.82

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Copyright © 2017 The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Fiber-optic scanning two-photon endomicroscope. The endomicroscope involved a single piece of DCF, and the mechanical assembly is illustrated in a; the inset is a photograph of the endomicroscope head (along with a ruler with 1-mm graduations) depicting the physical dimensions of the endomicroscope, which has an outer diameter of ~2.1 mm and a rigid length of ~35 mm. (b) Spectra of nonlinear in-fiber background emission from our customized DCF and two common types of commercial DCFs (SM-GDF-5/130 from NuFern and SMM900 from Fibercore), demonstrating the significantly reduced in-fiber background noise of our customized DCF.