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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: J Clin Pharmacol. 2017 Nov 14;58(1):7–24. doi: 10.1002/jcph.1028

Figure 7.

Figure 7

The use of targeted therapies in settings other than the treatment of cancer. The EGFR and its downstream signaling pathways play complex roles in numerous processes in addition to their roles in cancer. As a result, inhibitors of the EGFR and other targeted therapies are being tested systemically and locally for diverse applications. For example, targeted therapies are being evaluated as antiviral agents, vaccine adjuvants, to enhance wound healing, to promote nerve regrowth following nerve injury, and in other settings. EGFR indicates epidermal growth factor receptor.