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. Author manuscript; available in PMC: 2018 May 29.
Published in final edited form as: Am J Med Genet. 1996 Oct 16;65(2):137–141. doi: 10.1002/(SICI)1096-8628(19961016)65:2<137::AID-AJMG11>3.0.CO;2-R

Fig. 3.

Fig. 3

Quantitative hybridization using a radio-labeled PCR product generated using primers of exons 4 and 6 of the SNRPN gene [Ozcelik et al., 1992] with genomic DNA digested with Bgl II. The 7.5 kb (upper band) fragment represents a pseudogene (used as control) from chromosome 6 and the 5.8 kb (lower band) fragment represents the SNRPN gene from 15q11q13 region. Lanes 1 and 3 are from patient EE and show a submicroscopic deletion (e.g., calculated copy number of 0.7 or a deletion for SNRPN) of 15q11q13 and confirmed by FISH analysis. Lanes 2 and 4 are a normal control female.