Table 1.

Baseline data.

		LDN ×1	LDN ×2–3	LDN ×4+
N [%]	IBD [N = 582]	189 [32.5]	137 [23.5]	256 [44.0]
	Crohn’s disease [N = 139]	54 [38.8]	35 [25.2]	50 [36.0]
	Ulcerative colitis [N = 178]	54 [30.3]	43 [24.2]	81 [45.5]
Age in 2013 [± SD]	IBD	48.7 [± 16.0]	48.7 [± 13.5]	50.0 [± 13.7]
	Crohn’s disease	42.4 [± 14.6]	45.7 [± 14.3]	41.7 [± 13.3]
	Ulcerative colitis	44.7 [± 15.2]	45.5 [± 14.3]	48.7 [± 13.7]
Females [%]	IBD	152 [60.3]	119 [70.8]	210 [67.5]
	Crohn’s disease	32 [59.3]	30 [85.7]	31 [62.0]
	Ulcerative colitis	24 [44.4]	26 [60.5]	48 [59.3]
Users [2 years before first LDN prescription] of [%]
All drugs being studied	IBD	139 [73.5]	109 [79.6]	216 [84.4]
	Crohn’s disease	50 [92.6]	30 [85.7]	47 [94.0]
	Ulcerative colitis	49 [90.7]	37 [86.0]	79 [97.5]
Systemic glucocorticoids	IBD	71 [37.6]	60 [43.8]	107 [41.8]
	Crohn’s disease	25 [46.3]	19 [54.3]	26 [52.0]
	Ulcerative colitis	30 [55.6]	24 [55.8]	42 [51.9]
TNF α inhibitors	IBD	32 [16.9]	14 [10.2]	27 [10.5]
	Crohn’s disease	20 [37.0]	8 [22.9]]	10 [20.0]
	Ulcerative colitis	11 [20.4]	5 [11.6]	10 [12.3]
Other systemic immunosuppressants	IBD	29 [20.6]	23 [16.8]	45 [17.6]
	Crohn’s disease	22 [40.7]	10 [28.6]	21 [42.0]
	Ulcerative colitis	14 [25.9]	16 [37.2]	14 [17.3]
Aminosalicylates	IBD	89 [47.1]	58 [42.3]	139 [54.3]
	Crohn’s disease	22 [40.7]	12 [34.3]	22 [44.0]
	Ulcerative colitis	46 [85.2]	35 [81.4]	71 [87.7]
Intestinal corticosteroids	IBD	42 [22.2]	40 [29.2]	53 [20.7]
	Crohn’s disease	21 [38.9]	17 [48.6]	25 [50.0]
	Ulcerative colitis	16 [29.6]	19 [44.2]	21 [25.9]