Table 3.

Associations between comorbidity status and diagnosis of PC at follow-up

	PC	Cases	ORa	95% CI	P	Cases	ORb	95% CI	P
Hypertension	All	81	0.61	0.32, 1.17	0.14	79	0.72	0.37, 1.39	0.32
	High grade	33	0.77	0.33, 1.80	0.55	32	0.96	0.39, 2.35	0.93
	Low grade	48	0.54	0.26, 1.12	0.10	47	0.63	0.29, 1.34	0.22
Hypercholesterolemia	All	81	0.57	0.30, 1.10	0.09	79	0.52	0.26, 1.03	0.06
	High grade	33	0.43	0.18, 1.06	0.07	32	0.37	0.14, 0.98	0.04
	Low grade	48	0.71	0.34, 1.47	0.35	47	0.64	0.29, 1.39	0.26
Diabetes	All	81	0.94	0.33, 2.66	0.90	79	0.99	0.30, 3.16	0.98
	High grade	33	1.16	0.31, 4.30	0.82	32	1.18	0.29, 4.81	0.82
	Low grade	48	0.80	0.23, 2.82	0.72	47	0.74	0.17, 3.20	0.69
BPH	All	81	0.79	0.40, 1.53	0.48	79	0.87	0.43, 1.75	0.69
	High grade	33	1.13	0.48, 2.66	0.78	32	1.70	0.63, 4.62	0.30
	Low grade	48	0.60	0.29, 1.39	0.25	47	0.71	0.31, 1.60	0.40
Aspirin	All	81	0.73	0.38, 1.41	0.35	79	0.78	0.40, 1.53	0.47
	High grade	33	0.65	0.27, 1.55	0.33	32	0.60	0.24, 1.52	0.28
	Low grade	48	0.80	0.38, 1.69	0.56	47	0.87	0.40, 1.91	0.73
Statins	All	81	0.51	0.26, 0.98	0.04	79	0.45	0.23, 0.91	0.03
	High grade	33	0.45	0.19, 1.12	0.08	32	0.39	0.15, 1.04	0.06
	Low grade	48	0.56	0.27, 1.20	0.14	47	0.50	0.23, 1.12	0.09
Metformin	All	81	0.29	0.05, 1.50	0.14	79	0.32	0.06, 1.77	0.19
	High grade	33	0.31	0.03, 2.85	0.30	32	0.30	0.03, 2.96	0.30
	Low grade	48	0.26	0.03, 2.21	0.21	47	0.29	0.03, 2.64	0.27

aAdjusted for age.

bAdjusted for age, PSA and prostate volume.

High-grade PC: Gleason 7–10.