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. 2018 May 16;12:41. doi: 10.3389/fncir.2018.00041

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Copyright © 2018 Delcasso, Denagamage, Britton and Graybiel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Steps of HOPE-implant construction. (A) Insertion of the two polyimide-tube bundles into the shuttle. (B) Insertion of the shuttle into the body. (C) Insertion and cutting of the tetrodes. (D) Leveling of tetrode lengths. (E) Addition of the drive system (screw and bar) and the EIB. (F) Encapsulation of the implant.