Fig. 1.
IL-10 in PSA-experienced T cells is dispensable for protection against airway leukocyte infiltration. IL-10-null (IL-10n) mice were exposed to PSA or saline via oral gavage. PSA-experienced CD4+ T cells were harvested, and 2 × 106 cells were adoptively transferred into OVA-sensitized WT recipients. On Day 7 of OVA or saline challenge, mice were sacrificed and lungs lavaged with saline. Recovered cells were analyzed by a Hemavet counter and plotted. PSA-experienced IL-10n CD4+ T cells were able to prevent leukocyte infiltration into the airways. * = P < 0.05; # = P > 0.05. P value calculated from Student's T-test. Error bars show mean with SEM.