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. 2018 Apr 19;39(6):767–777. doi: 10.1093/carcin/bgy034

Figure 1.

Figure 1.

OPCs and GSE exert antitumorigenic properties in colorectal cancer cell lines. (A) Structural representation of basic monomeric units of proanthocyanidins. (B) Effect of OPCs and GSE on proliferation of six colorectal cancer cell lines treated for 72 h with 0–500 ng/ul of OPCs. (C) Cell-cycle analysis in HCT116 and SW480 cells treated with 100 ng/ul of OPCs or GSE. (D) Apoptosis in HCT116 and SW480 cells treated with 100 ng/ul of OPCs or GSE, shown as fold change with respect to control cells treated with vehicle (DMSO). *P < 0.05, **P < 0.01, ***P < 0.001 compared with control treatments.