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. 2018 May 23;38(Suppl 1):S16–S31. doi: 10.1080/20469047.2017.1409452

Table 2. Published WHO recommendations for antibiotic therapy for children >2 years presenting with suspected cholera.

Condition ‘Antibiotic of choice’ Alternative In addition
WHO Pocketbook Recommendations Cholera with severe dehydration [12,20] Tetracycline 12.5 mg/kg qid for 3 days Erythromycin 12.5 mg/kg qid for 3 days Zinc supplementation
or or 20 mg/kg for 10–14 days as soon as vomiting has ceased
Doxycycline (dosage not listed) Chloramphenicol 20 mg/kg IM qid for 3 days
or  
Cotrimoxazole (dosage not listed)
WHO 2010 PAHO Recommendations (Haiti outbreak) Option 1 Option 2  
Children over 3 years who can swallow tablets Erythromycin 12.5 mg/kg/6 h for 3 days Ciprofloxacin, suspension or tablets 20 mg/kg in a single dose  
or or
Azithromycin, 20 mg/kg in a single dose not exceeding 1 g doxycycline suspension or tablets 2–4 mg/kg PO in single dose
Children under 3 years, or infants who cannot swallow tablets Erythromycin, suspension, Ciprofloxacin suspension 20 mg/kg, in a single dose  
12.5 mg/kg/6 h for 3 days
or or
Azithromycin suspension 20 mg/kg in a single dose Doxycycline syrup 2–4 mg/kg PO in a single dose

Note: IM, intramuscular; qid, four times daily.